Charge-controlled treatment planning for tumor electroporation
This technology improves a cancer treatment method called irreversible electroporation (IRE), which uses electrical pulses to destroy tumors without heat. The system creates a personalized treatment plan for each patient by building a 3D computer model of the target tissue from medical images, then calculates the exact electrical parameters needed. It also uses a specific pulse design — bipolar pulses — that delivers the right therapeutic dose while avoiding collateral electrical damage to surrounding healthy tissue. The result is a more precise, safer ablation procedure tailored to the individual patient's anatomy.
What you could build
A software-driven treatment planning system for interventional oncologists performing irreversible electroporation procedures, sold as a clinical decision-support platform that integrates with existing imaging and ablation hardware; buyers would be hospitals and cancer centers using IRE systems such as NovaBay or AngioDynamics' NanoKnife.
Who in Virginia should care
Virginia academic medical centers (UVA Health, Inova) and defense-adjacent biomedical device companies in Northern Virginia with interests in precision energy delivery would be natural partners or licensees.
Readiness: Lab validated
Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.
Readiness is inferred from the patent text, not from a lab visit.
The record
- Inventors
- Robert E. Neal II, Paulo A. Garcia, Rafael V. Davalos, John H. Rossmeisl, John L. Robertson
- Filed
- Patent pending — filed January 14, 2025
- Status
- Application
- Publication number
- US20250228602A1
Ready to talk?
Virginia Tech Intellectual Properties handles licensing for this technology. Email us for an introduction prosim@harbor.capital.
Prosim summaries are generated from public patent text and are not legal advice.