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Patient-specific electroporation protocol optimizer for IRE

Biomedical DevicesComputing, Software & AIHealth & Safety TechConceptPatent pending

This technology is a treatment planning system for irreversible electroporation, a procedure that destroys tumors using electrical pulses rather than heat or surgery. The system builds a three-dimensional digital model of the patient's target tissue from medical images, then runs numerical simulations that account for the tissue's unique shape, density variations, and how it responds to electrical fields over time. The output is a customized treatment protocol — specifying electrode placement, pulse parameters, and timing — tailored to that specific patient's anatomy. A separate innovation addresses a known side effect: tissue damage from excess electrical charge, mitigated through carefully designed bipolar pulse delivery.

What you could build

A software-driven treatment planning platform for interventional oncologists performing irreversible electroporation (IRE) procedures, sold as a SaaS tool or bundled with electroporation hardware systems; buyers would be hospital cancer centers and the medical device companies that manufacture IRE systems like AngioDynamics.

Who in Virginia should care

Northern Virginia and Richmond-area academic medical centers, plus defense-adjacent biomedical device companies in the Hampton Roads corridor that serve dual-use therapeutic applications.

Readiness: Concept

Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.

Readiness is inferred from the patent text, not from a lab visit.

The record

Inventors
Robert E. Neal II, Paulo A. Garcia, Rafael V. Davalos, John H. Rossmeisl, John L. Robertson
Filed
Patent pending — filed October 29, 2024
Status
Application
Publication number
US20250120762A1

Ready to talk?

Virginia Tech Intellectual Properties handles licensing for this technology.

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Prosim summaries are generated from public patent text and are not legal advice.