Casein-depleting isolation kit for milk-derived exosomes
This technology describes a step-by-step process for cleanly extracting exosomes—tiny biological particles that carry proteins and other signals—from milk and similar fat-rich biological fluids. The challenge with milk is that it contains caseins, proteins that clump together and interfere with standard exosome isolation. The method solves this by first stripping out fats through centrifugation, then using a chelating agent (EDTA) to break apart casein clusters, and finally running the remaining fluid through filtration steps to yield a purified exosome fraction. The result is a reproducible laboratory protocol for getting usable exosomes out of a notoriously difficult source material.
What you could build
A standardized reagent kit and protocol for isolating milk-derived exosomes, sold to biotech researchers and nutraceutical companies exploring exosomes as drug delivery vehicles or bioactive ingredients in functional foods.
Who in Virginia should care
Virginia-based food science, dairy processing, or agricultural biotech companies, as well as contract research organizations serving nutraceutical or drug delivery clients, would be plausible partners or licensees.
Readiness: Lab validated
Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.
Readiness is inferred from the patent text, not from a lab visit.
The record
- Inventors
- Spencer MARSH, Kevin J. PRIDHAM, Linda Jane JOURDAN, Robert G. GOURDIE
- Filed
- Patent pending — filed August 22, 2023
- Status
- Application
- Publication number
- US20240131473A1
Ready to talk?
Virginia Tech Intellectual Properties handles licensing for this technology.
Prosim summaries are generated from public patent text and are not legal advice.