Broad-spectrum DNA-shuffled live-attenuated PRRSV vaccine
This technology provides a method for creating high-performance vaccines against the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), a major threat to the global swine industry. Researchers use a technique called DNA shuffling to combine the genetic strengths of multiple different virus strains into a single, 'chimeric' virus. This resulting virus is live but weakened, allowing it to trigger a broad immune response in pigs that protects against a wider variety of virus mutations than traditional vaccines. By engineering these specific proteins (GP2 through GP5 and M), the vaccine mimics the complexity of real-world outbreaks more effectively.
What you could build
A broad-spectrum modified live-attenuated vaccine (MLV) sold to industrial pork producers and veterinary pharmaceutical companies.
Who in Virginia should care
Virginia's substantial pork production industry and the presence of major animal health companies in the region make this highly relevant for local agricultural biosecurity.
Readiness: Lab validated
Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.
Readiness is inferred from the patent text, not from a lab visit.
The record
- Inventors
- Yanyan Ni, Yao-Wei Huang, Xiang-Jin Meng
- Granted
- September 15, 2015
- Status
- Granted patent
- Patent number
- 9132185
Ready to talk?
Virginia Tech Intellectual Properties handles licensing for this technology.
Prosim summaries are generated from public patent text and are not legal advice.