Region-of-interest SPECT reconstruction engine for lower-dose
This technology improves how SPECT scanners — a type of nuclear medicine imaging device — reconstruct internal images of the body. Instead of capturing data from the entire body, it focuses computation on a specific region of interest, using mathematical transforms to produce exact, stable images from that localized data alone. The method also incorporates a technique called high-order total variation minimization, which reduces image noise and artifacts. The practical result is sharper diagnostic images achieved with lower radiation doses and faster scan times.
What you could build
A software reconstruction engine licensed to SPECT scanner manufacturers (GE HealthCare, Siemens Healthineers, Philips) or integrated into third-party image-processing platforms to improve image quality and reduce radiation exposure in nuclear cardiology and oncology imaging.
Who in Virginia should care
Defense and government health facilities in Virginia — including military medical centers and NIH-adjacent imaging labs — as well as Inova or UVA Health imaging technology procurement teams.
Readiness: Lab validated
Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.
Readiness is inferred from the patent text, not from a lab visit.
The record
- Inventors
- Hengyong YU, Ge WANG, Ming JIANG, Jiansheng YANG
- Granted
- February 10, 2015
- Status
- Granted patent
- Patent number
- 8952333
Ready to talk?
Virginia Tech Intellectual Properties handles licensing for this technology.
Prosim summaries are generated from public patent text and are not legal advice.