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3D-bioprinted bacterial cellulose scaffolds for tissue

Biomedical DevicesBiotech & PharmaAdvanced MaterialsLab validated

This technology uses bacteria to grow three-dimensional cellulose structures with precisely controlled shapes, pore sizes, and thicknesses — essentially 3D printing with living microbes instead of plastic filaments. The process combines microfluidic nutrient delivery with inkjet-style bioprinting to guide bacterial cellulose growth around sacrificial alginate templates, which are later dissolved away to leave behind a porous, interconnected scaffold. The resulting nano-cellulose structures are strong, biocompatible, and architecturally tunable, making them suitable for use as tissue engineering scaffolds, surgical implants, or wound care materials. Think of it as growing a custom-shaped biological sponge that the human body can accept and potentially integrate with.

What you could build

A manufacturing process or contract fabrication service producing custom bacterial cellulose scaffolds for cartilage, bone, vascular, or wound-healing applications, sold to medical device companies and regenerative medicine researchers as ready-to-use implantable components or research tools.

Who in Virginia should care

Virginia-based medical device manufacturers, defense medical research programs (DARPA, USAMRIID at Fort Detrick proximity), and university hospital systems with regenerative medicine programs would be plausible partners or licensees.

Readiness: Lab validated

Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.

Readiness is inferred from the patent text, not from a lab visit.

The record

Inventors
Paul Gatenholm, Henrik Backdahl, Theodore Jon Tzavaras, Rafael V. Davalos, Michael B. Sano
Granted
April 8, 2014
Status
Granted patent
Patent number
8691974

Ready to talk?

Virginia Tech Intellectual Properties handles licensing for this technology.

VTIP contact coming shortly

Prosim summaries are generated from public patent text and are not legal advice.