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Abscisic acid compound targeting PPAR-gamma for diabetes

Biotech & PharmaAgriculture & Food SystemsHealth & Safety TechLab validated

This patent covers the use of abscisic acid (ABA) — a naturally occurring plant hormone also found in mammals — as a therapeutic agent for metabolic and inflammatory diseases. ABA works by activating a protein called PPAR-gamma, which plays a central role in regulating insulin sensitivity, fat storage, and immune cell behavior. By modulating this pathway, ABA can reduce the infiltration of inflammatory immune cells into fat and muscle tissue, a key driver of type 2 diabetes and obesity-related inflammation. The invention covers administering ABA in various forms, alone or in combination with other treatments, to address conditions ranging from type 2 diabetes and prediabetes to inflammatory bowel disease, multiple sclerosis, and arthritis.

What you could build

A nutraceutical supplement or pharmaceutical compound containing ABA targeting patients with type 2 diabetes, prediabetes, or obesity-related inflammation; buyers would include specialty pharma companies, functional food and supplement brands, and potentially biotech licensees pursuing PPAR-gamma-pathway drugs.

Who in Virginia should care

Virginia-based pharmaceutical and biotech firms, as well as dietary supplement companies in the mid-Atlantic corridor, would be plausible licensees or development partners.

Readiness: Lab validated

Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.

Readiness is inferred from the patent text, not from a lab visit.

The record

Inventors
Josep BASSAGANYA-RIERA, Amir GURI, Raquel HONTECILLAS
Granted
June 22, 2010
Status
Granted patent
Patent number
7741367

Ready to talk?

Virginia Tech Intellectual Properties handles licensing for this technology.

VTIP contact coming shortly

Prosim summaries are generated from public patent text and are not legal advice.