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Dry-powder amphiphilic polysaccharide hydrogel kit for

Biotech & PharmaAdvanced MaterialsBiomedical DevicesLab validated

This technology describes new ways to chemically modify natural polysaccharides—sugars found in plants and microbes—to make them amphiphilic (able to interact with both water and oils) or to turn them into hydrogels, which are water-swollen gel networks. The core innovation is a cleaner, more controlled synthesis process that attaches specific chemical groups to the sugar backbone, ending with ketone-bearing polysaccharides that can cross-link with amine-bearing partners to form gels on demand. The resulting hydrogels can be dried into a solid powder, stored, and then reconstituted with water later—a practical advantage for shipping and shelf life. These materials are derived from renewable, biodegradable starting materials like dextran, making them attractive for sustainable product development.

What you could build

Injectable or topically applied biocompatible hydrogel kits—sold as dry powders that form gels on mixing—for wound care, drug delivery matrices, or tissue engineering scaffolds; buyers would be medical device companies, pharmaceutical formulators, and regenerative medicine startups.

Who in Virginia should care

Virginia-based pharmaceutical contract manufacturers, biotech startups in the Northern Virginia/DC corridor, and university med-school research programs would be natural early adopters or licensing partners.

Readiness: Lab validated

Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.

Readiness is inferred from the patent text, not from a lab visit.

The record

Inventors
Kevin J. Edgar, Brittany L.B. Nichols, Junyi Chen, Charles Frazier, Lynne S. Taylor, Laura I. Mosquera-Giraldo, Ann Norris
Granted
December 10, 2024
Status
Granted patent
Patent number
12162962

Ready to talk?

Virginia Tech Intellectual Properties handles licensing for this technology.

VTIP contact coming shortly

Prosim summaries are generated from public patent text and are not legal advice.