Biphasic pulse ablation system for non-thermal soft-tissue
This technology is a medical device that destroys unwanted tissue — such as tumors — using precisely controlled electrical pulses without generating heat, a technique called irreversible electroporation. The device delivers rapid alternating-polarity pulses at high voltage, which kills targeted cells while reducing the collateral damage typically caused by heat or excess electrical charge. Critically, it uses 3D imaging of the patient's tissue to calculate a customized treatment plan before the procedure begins, accounting for the unique geometry and properties of each patient's anatomy. This combination of personalized planning software and a purpose-built pulse generator represents an end-to-end ablation system.
What you could build
A clinical ablation system — hardware generator plus treatment-planning software — sold to hospitals and interventional oncology centers for minimally invasive destruction of soft-tissue tumors, particularly in sensitive locations near critical structures like blood vessels or bile ducts.
Who in Virginia should care
Interventional oncology programs at major Virginia health systems (Inova, VCU Health, UVA Health) and medtech device companies in the Northern Virginia/DC corridor would be plausible partners or licensees.
Readiness: Prototype likely
Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.
Readiness is inferred from the patent text, not from a lab visit.
The record
- Inventors
- Robert E. Neal II, Paulo A. Garcia, Rafael V. Davalos, John H. Rossmeisl, John L. Robertson
- Granted
- April 9, 2024
- Status
- Granted patent
- Patent number
- 11952568
Ready to talk?
Virginia Tech Intellectual Properties handles licensing for this technology.
Prosim summaries are generated from public patent text and are not legal advice.