Biphasic high-frequency pulse generator for safer tumor
This technology is a precision tumor-destruction system that uses carefully timed bursts of alternating electrical pulses to kill cancer cells without generating damaging heat. A computer model first builds a 3D reconstruction of the patient's tumor from medical images, then calculates the exact pulse parameters needed to destroy it based on that specific patient's anatomy. The electrical pulses are delivered at very high frequency with controlled polarity switching, which eliminates the muscle contractions and collateral tissue damage that have limited older electroporation-based treatments. The result is a more controllable, patient-tailored ablation procedure that can reach tumors in locations where surgery or thermal ablation would be too risky.
What you could build
A software-guided ablation system sold to interventional oncology suites and hospitals performing minimally invasive tumor treatment, combining pre-procedure patient-specific modeling software with a high-frequency biphasic pulse generator and probe set; buyers are hospitals, cancer centers, and medical device OEMs seeking to license the waveform and planning technology.
Who in Virginia should care
Virginia cancer centers (Inova, UVA Health, VCU Massey) and medical device companies in the Northern Virginia and Richmond corridors would be plausible partners or licensees.
Readiness: Prototype likely
Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.
Readiness is inferred from the patent text, not from a lab visit.
The record
- Inventors
- Rafael V. Davalos, Paulo A. Garcia, John H. Rossmeisl, John L. Robertson, Robert E. Neal II
- Granted
- September 27, 2022
- Status
- Granted patent
- Patent number
- 11453873
Ready to talk?
Virginia Tech Intellectual Properties handles licensing for this technology.
Prosim summaries are generated from public patent text and are not legal advice.