High-frequency electroporation ablation without general
This technology uses precisely timed bursts of high-frequency electrical pulses to kill cancer cells inside the body. Unlike conventional electroporation, which can cause painful muscle contractions and collateral nerve damage, the high-frequency bipolar pulses cancel out unwanted electrical stimulation of nerves and muscles while still destroying tumor cells. The pulses can work either by opening permanent holes in cell membranes (irreversible electroporation) or by enhancing uptake of cancer-killing drugs (electrochemotherapy). It is designed to treat solid tumors, including difficult targets like brain tumors, with a minimally invasive probe.
What you could build
A clinical ablation device—probe plus pulse generator—that oncologists and interventional radiologists use to destroy solid tumors without the anesthesia burden and collateral tissue risks of current electroporation systems; hospitals, cancer centers, and medical device companies targeting surgical oncology would be the buyers.
Who in Virginia should care
Virginia's academic medical centers (UVA Health, VCU Health, Inova) and medical device companies in the Northern Virginia/Richmond corridor with oncology or interventional device programs would be natural partners or licensees.
Readiness: Prototype likely
Concept — described but not yet demonstrated. Lab validated — supported by experimental results in the patent. Prototype likely — the text describes a built, working embodiment.
Readiness is inferred from the patent text, not from a lab visit.
The record
- Inventors
- —
- Granted
- May 21, 2019
- Status
- Granted patent
- Patent number
- 102830
Ready to talk?
Virginia Tech Intellectual Properties handles licensing for this technology.
Prosim summaries are generated from public patent text and are not legal advice.